Many people would prefer not to take prescription medications if it is not absolutely necessary. Though Zoloft is ideal for some people, many can achieve the same benefits from Zanaprin, the non-prescription Zoloft alternative , therefore avoiding the much more dramatic side effects of the more powerful medications. For example, many prescription SSRI’s can build a significant addiction within the body, meaning that it can be very challenging to stop their use. In fact, it can be miserable or even painful to get off a prescription anti-anxiety medication if it has not been done properly. Furthermore, there are many other heavy side effects such as insomnia, diarrhea, dry mouth, and sleepiness that are often associated with prescription medications of this nature.