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In 2007 the pharmaceutical company GTx, Inc was conducting two different phase 3 clinical trials ; First, a pivotal Phase clinical trial for the treatment of serious side effects of androgen deprivation therapy (ADT) (especially vertebral/spine fractures and hot flashes , lipid profile, and gynecomastia ) for advanced prostate cancer, and second, a pivotal Phase III clinical trial for the prevention of prostate cancer in high risk men with high grade prostatic intraepithelial neoplasia , or PIN. Results of these trials are expected by first quarter of 2008 [2]

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